Association of family history of cardiometabolic diseases (CMDs) and individual health behaviours: Analysis of CARRS study from South Asia

Objectives: Family history is considered as an important predictor of cardiovascular diseases (CVDs) and diabetes. Available research findings suggest that family history of chronic diseases is associated with perceived risk of disease and adoption of healthy behaviours. We examined the association between family history of cardio-metabolic diseases (CMDs) and healthy behaviours among adults without selfreported CMDs. Methods: Cross-sectional data of 12,484 adults, without self-reported CMDs, from the baseline survey of Centre for cArdiometabolic Risk Reduction in South-Asia (CARRS) cohort study were analysed. Results: Family history was positively associated with non-smoking and high fruits & vegetables consumption in the age group of 45e64 years and moderate to high physical activity in the age group _x0001_65 years after adjusting for sex, education, wealth index, city and body mass index. Conclusions: Understanding perceived risks and cultural or psychological factors related to family history through ethnographic studies may deepen understanding of these associations.

Enfermedades cardiometabólicas y la mortalidad por el COVID-19 en el inicio de la pandemia en Colombia / Cardiometabolic Diseases and Mortality due to COVID-19 During the Pandemic's Onset in Colombia / Doenças cardiometabólicas e mortalidade por COVID-19 no início da pandemia na Colômbia

Resumen: el escenario de la pandemia actual derivada del COVID-19, infección causada por el virus denominado SARS-CoV-2, ha permitido develar la interacción entre enfermedades infecciosas y enfermedades crónicas no transmisibles, de manera que ha aportado hallazgos que sugieren un aumento en las tasas de mortalidad por COVID-19. El objetivo de este artículo es describir las características sociodemográficas y de morbilidad en los fallecimientos ocurridos en Colombia por COVID-19 al 19 de mayo del 2020. Es un estudio descriptivo a partir de reportes del Instituto Nacional de Salud, sobre fallecimientos de casos positivos por COVID-19, del 6 de marzo al 19 de mayo del 2020. La información sobre factores preexistentes se obtuvo de reportes del periódico El Tiempo en notas de prensa publicadas al respecto. Se realizó análisis descriptivo en Excel y SPSS v25. Se identificaron 613 fallecimientos en el periodo. El mayor número de muertes ocurrió en Bogotá D. C. (35,0 %), seguida de Valle de Cauca (10,4 %), Cartagena (8,6 %), Amazonas (7,2 %) y Meta (5,6 %). La edad promedio de las defunciones fue 67,26 ± 16,28 años, siendo el grupo de edad de 60-79 años en el que más muertes se presentaron, con el 50,7 % de los casos. El 60,8 % de las defunciones ocurrió en personas de sexo masculino, y un 80,1 % tenían alguna morbilidad: 36,2 % padecía hipertensión, 19,2 % diabetes mellitus, 17,1 % EPOC, 16,5 % alguna enfermedad cardiovascular, 11,1 % obesidad y un 16,2 % padecía otro tipo de enfermedad sin especificar. El antecedente de morbilidad por patologías cardiometabólicas asociadas con factores alimentarios y nutricionales favorece la mortalidad en personas infectadas por COVID-19 en Colombia.

Abstract: the current scenario derived from the COVID-19 Infection caused by the virus denominated SARS-CoV-2 has uncovered the interaction between infectious diseases and chronic non-communicable diseases, thus providing findings that suggest an increase in covid-19 mortality rates. The objective of this article is to describe the sociodemographic and morbidity characteristics of deaths occurring In Colombia due to COVID-19 as at May 19,2020. This Is a descriptive study based on reports from the National Institute of Health, on deaths of positive cases due to COVID-19, from March 6 to May 19, 2020. Information on pre-existing factors was obtained from reports on the newspaper El Tiempo in press releases published on the subject. Descriptive analysis was performed in Excel and SPSS v25. 613 deaths were Identified In the period. The highest number of deaths occurred in Bogota D. C. (35.0%), followed by Valle de Cauca (10.4%), Cartagena (8.6%), Amazonas (7.2%) and Meta (5.6%). The average age of the deaths was 67.26 ± 16.28 years, with the 60-79 age group accounting for 50.7 % of the deaths. A total of 60.8 % of the deaths occurred In males, and 80.1 % had some form of morbidity: 36.2% suffered from hypertension, 19.2% from diabetes mellitus, 17.1 % EPOC, 16.5% some cardiovascular disease, 11.1 % obesity and 16.2% other type of unspecified disease. The history of morbidity due to cardiometabolic pathologies associated with dietary and nutritional factors favors mortality In persons infected by COVID-19 in Colombia.

Resumo: o cenário da atual pandemia decorrente da COVID-19, Infecção causada pelo virus chamado SARS-CoV-2, revelou a interação entre doenças Infecciosas e doenças crónicas não transmissíveis, de modo que tem fornecido achados que sugerem um aumento nas taxas de mortalidade por COVID-19. O objetivo deste artigo é descrever as características sociodemográficas e de comorbidade das mortes na Colombia por COVID-19 até o día 19 de maio de 2020. Trata-se de um estudo descritivo baseado em relatórios do Instituto Nacional de Saúde, sobre mortes de casos positivos para COVID-19, de 6 de março a 19 de maio de 2020. Informações sobre fatores pré-existentes foram obtidas de reportagens do jornal El Tiempo em comunicados à imprensa sobre o assunto. A análise descritiva foi realizada no Excel e no SPSS v25. Foram identificadas 613 mortes no período. O maior número de mortes ocorreu na cidade de Bogotá D. C. (35,0 %), seguida por Valle de Cauca (10,4 %), Cartagena (8,6 %), Amazonas (7,2 %) e Meta (5,6 %). A média de idade dos óbitos foi de 67,26 ± 16,28 anos, em que a faixa etária de 60 a 79 anos teve mais óbitos, com 50,7 % dos casos. 60,8 % dos óbitos ocorreram no sexo masculino, e 80,1 % apresentaram alguma comorbidade: 36,2 % sofriam de hipertensão, 19,2 % diabetes mellitus, 17,1 % DPOC, 16,5 % doenças cardiovasculares, 11,1 % obesos e 16,2 % tinham outra doença não especificada. A história de comorbidade por patologias cardiometabólicas associadas a fatores alimentares e nutricionais favorece a mortalidade em pessoas infectadas com COVID-19 na Colômbia.

Bases para el diseño de una política pública para la educación nutricional en enfermedades cardiometabólicas en el Municipio Maracaibo, Estado Zulia / Bases for the design of a public policy for nutritional education in cardiometabolic diseases in the municipality of Maracaibo, Zulia state

Las enfermedades cardiometabólicas son de alta prevalencia en edades donde existe una mayor productividad. Esta condición representa un problema público que implica su análisis en el ámbito de las políticas públicas localizadas en contextos específicos como el caso del Municipio Maracaibo del Estado Zulia en Venezuela. El estudio propone elaborar el diseño de una política pública relativa a la educación nutricional, mediante la gestión de proyectos estratégicos para prevenir, educar y controlar las referidas enfermedades. El estudio fue desarrollado durante el período 2019-2020. En lo metodológico se fundamentó en el enfoque de marco lógico que permiten cuestionar y analizar la realidad estudiada, a través de la organización de un diseño de investigación estructurado en un nivel prospectivo-estratégico que implica la sistematización del problema público. El resultado plantea un proyecto didáctico de intervención comunitaria orientado a disminuir la prevalencia de enfermedades cardiometabólicas en esta región del país, mediante un programa de educación nutricional para promocionar estilos de vida saludables. Se concluye que la definición de las enfermedades cardiometabólicas como problema estructurado en el ámbito social, es un prerrequisito para el diseño de una política pública, asociado a proyectos de educación nutricional que contribuyan a atenuar esta condición en la población(AU)

Cardiometabolic diseases are highly prevalent at ages where there is greater productivity. This condition represents a public problem that implies its analysis in the field of public policies located in specific contexts, such as the Maracaibo Municipality of the Zulia State - Venezuela. The study proposes to develop the design of a public policy related to nutritional education, through the management of strategic projects to prevent, educate and control the referred diseases. The study was developed during the 2019- 2020 period. Methodologically, it was based on the logical framework approach that allows questioning and analyzing the reality studied, through the organization of a structured research design at one level; prospective - strategic, and implies the systematization of the public problem. The result proposes a didactic community intervention project aimed at reducing the prevalence of cardiometabolic diseases in this region of the country, through a nutritional education program to promote healthy lifestyles. It is concluded that the definition of cardiometabolic diseases as a structured problem in the social sphere is a prerequisite for the design of a public policy, associated with nutritional education projects that contribute to mitigating this condition in the population(AU)

Comparison of scores for the classification of cardiometabolic risk in adult patients enrolled in a Venezuelan program for chronic non-communicable diseases: a cross-sectional study

ABSTRACT BACKGROUND: Several continuous measurements of cardiometabolic risk (CMR) have emerged as indexes or scores. To our knowledge, there are no published data on its application and validation in Latin America. OBJECTIVE: To evaluate four continuous measurements of metabolic status and CMR. We established its predictive capacity for four conditions associated with CMR. DESIGN AND SETTING: Cross-sectional study conducted at a healthcare center in the state of Carabobo, Venezuela. METHODS: The sample comprised 176 Venezuelan adults enrolled in a chronic disease care program. Four CMR scores were calculated: metabolic syndrome (MetS) Z-score; cardiometabolic index (ICMet); simple method for quantifying MetS (siMS) score; and siMS risk score. CMR biomarkers, proinflammatory status and glomerular function were assessed. MetS was established in accordance with a harmonized definition. RESULTS: Patients with MetS showed higher levels of all scores. All scores increased as the number of MetS components rose. The scores showed significant correlations with most CMR biomarkers, inflammation and glomerular function after adjusting for age and sex. In the entire sample, MetS Z-score, siMS score and siMS risk score showed the ability to detect MetS, reduced glycemic control, proinflammatory status and decreased estimated glomerular filtration rate. ICMet only discriminated MetS and proinflammatory state. There were some differences in the predictive capacity of the scores according to sex. CONCLUSIONS: The findings support the use of the scores assessed here. Follow-up studies should evaluate the predictive capacity of scores for cardiovascular events and diabetes in the Venezuelan population.

Importancia nutricional y actividad biológica de los compuestos bioactivos de quelites consumidos en México / Nutritional importance and biological activity of bioactive compounds from quelites consumed in Mexico

Sólo un 30% de los hogares en México, presentan seguridad alimentaria, es decir, un gran porcentaje de los hogares y por ende de la población no satisfacen las necesidades básicas diarias de macro y micronutrimentos. Los quelites, que se definen como plantas silvestres comestibles (hojas, tallos y flores) son una fuente accesible, continua, económica y adecuada de nutrimentos. Sin embargo, su consumo ha disminuido por modificaciones en las preferencias alimentarias, derivadas de los cambios en estilos de vida. El objetivo del presente trabajo fue valorizar a los quelites como fuente de alimento. Los quelites, aportan proteínas, aminoácidos, minerales (Ca, Mg, Zn), vitaminas (E, C) y fibra. Además, son una excelente fuente de compuestos bioactivos, como ácidos fenólicos (ácido cafeico, ferúlico) y flavonoides (quercetina, kaempferol, espinacetina), carotenoides, ácido α-linolénico y betalainas, que presentan elevada actividad antioxidante. Su consumo habitual se ha relacionado con beneficios a la salud, tales como efectos antitumorales, antihiperlipidémicos y antidiabéticos. Los quelites, además de estar disponibles en forma silvestre, forman parte de las tradiciones culinarias de México, incorporados de forma cruda y cocida en los platillos regionales. Por lo tanto, la revalorización y reincorporación de los quelites en la dieta, puede coadyuvar a cubrir las necesidades nutrimentales, en poblaciones con poco acceso o inseguridad alimentaria, además de contribuir a proporcionar efectos adicionales a través de sus compuestos bioactivos.

Only 30% of households in Mexico present food security, which means a large percentage of households and the population does not meet their needs in terms of macro and micronutrients. Thus, quelites, which are defined as wild edible plants, are an accessible, continuous, economical and adequate source of nutrients. However, quelite consumption in Mexico has been decreasing in response to changes in food preferences and lifestyles, including increased exposure to hypercaloric foods. Therefore, the aim of this work was to discuss the value of quelites as a food source rich in nutrients, proteins, amino acids, minerals (Ca, Mg, Zn), vitamins (E, C) and fiber. We also discuss how quelites are good source of bioactive compounds, such as phenolic acids (caffeic acid, ferulic acid) and flavonoids (quercetin, kaempferol, spinacetin), carotenoids, α-linolenic acid and betalaines. There use have been mainly related to the anti-tumor, antihyperlipidemic and antidiabetic benefits. We further discuss topics related to the culinary traditions of Mexico and the incorporation of quelites in the raw and cooked form in regional markets. The revaluation and the reincorporation of quelites in the diet can help meet nutritional needs, in addition to possibly providing additional health benefits.

Research progress of branched-chain amino acid in cardiometabolic diseases / 中华内分泌代谢杂志

The prevalences of cardiometabolic diseases such as obesity, insulin resistance are rising. Abnormal metabolisms of glucose and lipid are associated with cardiometabolic diseases. The amino acids are also play important roles in cardiometabolic diseases. Branched-chain amino acids are important essential amino acids, and studies about branched-chain amino acids in cardiometabolic diseases are rising. In this review we aimed to investigate the progress of branched-chain amino acids in cardiometabolic diseases.

Low indices of overweight and obesity are associated with cardiometabolic diseases among adult Filipinos in a rural community / Journal of the ASEAN Federation of Endocrine Societies

@#<p style="text-align: justify;"><strong>OBJECTIVES:</strong> To determine cut-off levels of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) for overweight/obesity associated with cardiometabolic diseases (CMDs) among adult Filipinos in a rural community.<br /><strong>METHODOLOGY:</strong> This community-based cross-sectional observational study utilized data from our Phase II of Diabetes Self-Management Education Program in San Juan, Batangas, Philippines. It included 332 Filipino adults with no known illnesses and residing for at least 6 months in the rural communities. Optimal cut-offs were determined by the intersection of sensitivity and specificity curves of having at least 1 or 2 CMDs.<br /><strong>RESULTS:</strong> The study population included 332 participants (72.3% females). Mean BMI, WC and WHR were 23.5 kg/m2, 79.5 cm and 0.87 respectively. Twenty eight percent, 11.1%, 78.3% and 85.8% of the participants have hypertension, diabetes, dyslipidemia, and at least 1 CMD respectively. The optimal cut-off for overweight/obesity and central obesity in males and females are BMI of 24 and 23 kg/m2, WC of 84 and 77 cm, and WHR 0.91 and 0.85 respectively.<br /><strong>CONCLUSION:</strong> Similar to other Asian countries, cut-off levels for overweight, obesity, and central obesity associated with CMDs are lower than the currently recommended cut-offs among Filipino adults in rural communities, particularly for WC in both sexes.</p>

Our Experiences With Human Body Composition Estimations; Low Discriminatory Power Of Body Mass Index To Segregate Body Fatness

Body mass index, though globally a very popular and frequently used surrogate measure of body fatness, has come under some scrutiny and serious criticism in recent years for its inability to reflect the same. This is particularly disconcerting with health risks involved in cardiometabolic diseases associated with obesity. Therefore, it is suggested that actual measurement of body fat levels be used and there are simple and easier techniques available. The measurements of body volume index in replacing body mass index may provide better information on human body composition for future research.

Prospective cohort studies of cardiometabolic diseases in China and the U. S / 中华内分泌代谢杂志

Cohort studies are important observational epidemiological studies. In this perspective, we briefly introduced several ongoing prospective cohort studies of cardiometabolic diseases in China and in the U. S. , which have shaped our current understanding of cardiometabolic diseases. We hope that this perspective could shed lights on the research of chronic diseases such as diabetes and cardiovascular diseases.